Recommend that you maintain a low or moderate doses of a drug or use a different ? fluctuating ? dose and carry fractional short-course therapy with the so-called drug holidays. Subject to the general WHO recommendations on limiting the duration of the use of hypnotics 46 weeks need to know the rules for its abolition in chronic use. Cancellation of the drug in this case should be conducted within 12 months. Reasonable rate of decrease in dose, which should be observed, is approximately 25% of the dose for a quarter of the period of his withdrawal (for example, if the period of cancellation is 4 weeks, then decrease the dose should be carried out at a rate of 25% per week). When carrying out lifting an effective drug to a simultaneous accession of other therapeutic strategies (placebo, sleep hygiene, relaxation techniques of psychotherapeutic techniques, biofeedback, stimulation of control, sleep restriction, cognitive therapy, etc.), as well as take into account the potential for the development of other alternative coping strategies with insomnia (alcoholism, substance abuse, etc.). Thus, the current state of pharmacovigilance hypnotics market allows them the choice to give the advantage of the newest drugs (third generation), synthesized according to the latest advances in molecular biology and pharmacology and have some significant advantages over older drugs. Published with permission from Russian Medical Journal.
Treatment of psycho-vegetative disorders
PhD IS Transfiguration MMA behalf IM Sechenov PhD AV Moskvin Research Center for Psy-System, Moscow The term "psycho-vegetative disorders" combines many symptoms, the most common of which are anxiety, internal tension, sleep disturbances, irritability, inadequate, and different modalities of emotional reactions. Often there are also so-called paroxysmal psychovegetative disorders - phobias, panic attacks. Description of such violations have occurred repeatedly in the artistic and the medical literature for centuries. Thus, already in 1894, Freud in the justification of separation from neurasthenia certain syndromes: anxiety neurosis pointed to specific clinical manifestations of psycho-vegetative disorders, in particular, indicating that anxiety and panic, as the maximum degree of its severity, may be associated with the violation of one or multiple functions. In this case, the patient may experience palpitations, compressing the throat, feeling short of breath, pain in the heart and so on. Currently, one can observe a significant prevalence in the population of these violations, which may be associated with an intense rhythm of modern life, as well as reduced stress tolerance in a time deficit, the excess of information as a consequence of rapid urbanization.
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