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This indicates that the connection between chronic physical illness with anxiety occurs more easily than with other psychiatric disorders, including depression. Secondary to physical illness of GAD occurs later than the first, the severity of his time varies depending on the exacerbation or remission of physical illness, anxiety disappears after the treatment of somatic diseases [35]. GAD should promptly identify and treat because it worsens the prognosis of concomitant somatic diseases [80]. However, the presence of somatic disease reduces the likelihood of a diagnosis of GAD as an independent disease: doctors regard the increased anxiety, such as diabetes as a "normal", justified by severe somatic pathology, therefore the diagnosis of GAD is not formulated and appropriate treatment is not carried out [12]. What are the physical problems most clearly conjugate with GAD? Women with GAD disease of the gastrointestinal tract observed in 62.5%, allergies - 52%, lower back pain - 50%, headache - 42%, metabolic disease - 27%. The presence of GAD and / or panic disorder ever lifetime increases the likelihood of heart disease (including CHD) in 5,9 times, the gastrointestinal tract - in 3,1 times, respiratory diseases and migraine - 2,1 times, hypertension, infections and skin diseases - in 1,7 times, diseases of the joints - in 1,6 times, the kidneys - in 1,5 times, metabolism - a 1.25-fold, allergic diseases - in 1,2 times [36]. Established that GAD in 62% of cases precedes the development of heart disease, about half the cases of GAD occurs before, and half - after a kidney disease, respiratory system and migraine. These data do not suggest a causal link and, most point to the existence of common predisposing factors. The importance of GAD in Cardiology is supported by a prospective 32-year study [44], which showed that the presence of elevated anxiety increases the likelihood of a fatal myocardial infarction in 1,9 times, sudden death - in 4,5 times. Perhaps this is due to typical alarm activation of the sympathetic nervous system and vagal tone, leading to the development of ventricular arrhythmias [20]. It can also play a role more prominent deviations atherogenic risk profile in anxious patients with coronary artery disease (higher BMI, percentage body fat, triglycerides and lower concentrations of HDL cholesterol) compared to patients with coronary artery disease without increased anxiety [57]. Sufficiently high comorbidity of GAD and neurological diseases. The frequency of early-GAD in patients with acute stroke, reaches 27%, GAD late (after 3 months) - 23%. 3 years after stroke, the prevalence of GAD is not reduced, while three-quarters of stroke patients with GAD and depression there. The presence of GAD was significantly worse during the depression, functional and social recovery of stroke patients.