Without a clear seasonality.

Complaints of heartburn, mild nausea, short sleep at night occurred in the first few days after reaching a therapeutic dose without additional appointments lost their relevance to the end of the course is not renewed. Paxil does not cause somnolentnosti day, which reduced the expression of apathy and lethargy, not cause internal discomfort. We have reflected clinical and pathological features of the observed depressions Table 1 Patient, age, diagnosis (ICD -10) disease duration previous depressive episodes nye Peculiarities of clinical features of this episode A., age 67, recurrent depressive disorder, current episode of moderate severity with somatic symptoms of "F 33.10 14 2 - mild, last - moderate Demonstration against pathological Klimakov-sa. Pronounced seasonality. The trend towards shortening of remission (from 7 am to 2 years old), weighting and elongation Niya monopolar attacks with adjoining somatic symptoms typical melancholic triad of moderate severity with the daily fluctuations, vital anguish, mental anesthesia, overvalued ideas of inferiority, somatic symptoms ( loss of appetite, insomnia, constipation, fluctuations in the A / D, weight loss of 4 kg), a formal critique. B., 1951, "Shizoaffek-tive disorder, mixed (bipolar) type" F 25.21 1 year 2 with severe multiple-governmental suitsidal-governmental attempts to Manifestation in involution period. Without a clear seasonality. With the inversion of depressive phases in hypomania. A continuous type of flow with the accession psihoproduktivnoy symptoms Upatoi adynamic depression with severe idiatornoy retardation, substuporom without the possibility of a productive contact, delusions, self-deprecation, guilt, persistent suicidal attempts, and the lack of criticism. VI, 51, 'recurrent depressive disorder, an episode of heavy formula degree of psychotic symptoms-mi on organically modified background. " F 33.38 4 years 4-to-moderate severity of suicidal thoughts manifestation after 3-CCT against pathological electric climax. Pronounced seasonality. The trend towards shortening of remission (from 1 till 3 months.) Elongation (up to 8 months.) Deepening of atypical depression, with alternation of agitation and melancholic lethargy Severe depressive episode with the speech-motor-inhibited up to a substupora, vital depersonalization, anguish , anxiety, emotional anesthesia, anhedonia, delusions, self-deprecation, guilt, persistent suicidal thoughts, lack of criticism. Somatic symptoms (poor appetite, insomnia, constipation, vibration A / D, weight loss of 6 kg.), The greatest interest from our point of view, observation, showing a sharp disinhibiting effect of Paxil. Patient B, on the background of many months of active therapy (amitriptyline, Melipraminum intravenously in combination with prodepom inside) remained in a state of apathy, pronounced adynamic depression. Paxil as monotherapy rapidly campaign increased from 20 mg to 60 mg for 2 days.