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Throughout the course of treatment recommended supportive counseling. In this case the doctor needs thoughtful advice on the duration of treatment, changes in dose levels, abstinence from alcohol. In all cases the purpose of pharmacotherapy doctor can make a good faith attempt to treat one drug, and then - switch to another group of drugs, or even (if necessary) at the third, until you reach the therapeutic effect. In the difficult differential diagnostic situations, or in the absence of the expected result of pharmacotherapy (with adequate doses for an adequate period of time), patients should be conducted in consultation with a psychiatrist, and perhaps even give him a patient for the full supervision. In difficult cases, when the competence of general practitioners is not enough, it is necessary to refer the patient to a specialized hospital (Fig. 2). The most common difficulties include: signs of suicide risk, severe, disabling or atypical forms of the disease, anxiety, manifest as a manifestation of schizophrenia or other procedure-induced disorders, complications of the disease alcoholism, personality disorders or other factors. Figure 2. Algorithm for treatment of anxiety as a general practitioner An indispensable key to the success of treatment-resistant anxiety disorders is a comprehensive approach that includes pharmacotherapy, along with a full wide range of psychotherapy, physiotherapy and social rehabilitation. Rich experience in complex treatment of patients with anxiety disorders has accumulated in a specialized hospital № 8 named. ZP Solov'ev - Clinic neurosis "[8]. A wide range of therapeutic and diagnostic interventions provides a subtle interweaving of countervailing influences, whose ultimate goal is to break stereotypes and pathological compensation painful manifestations (Fig. 3). Thus achieved and successfully promote the integration of psychiatric and somatic services, creating favorable conditions for solving therapeutic problems in patients suffering from anxiety disorders. Figure 3. Model of integrated treatment of anxiety disorders in Moscow "Clinic neuroses" Human nature demonstrates an interesting duality: sometimes it lands itself to a mechanistic interpretation, equating to some human solid substrate and functions of the organism, in other cases, involves a boundless field of consciousness, which unites matter, space, time and linear causality. Based on this, no one doubts even postulated the principle of Socrates: "You can not heal the body, not vrachuya soul." Does not lose its urgency and a statement of Freud that the task of therapy is the translation of "undue hardship neurosis in the ordinary tribulations of everyday life." References 1. Alexander's YA, BARDENSTEIN LM Avedisova A.