The study of this phenomenon in recent years in the world paid much attention, and it can be considered the eleventh feature. According to different authors, from 25 to 40% of outpatients violate the therapy so much that it significantly affects the effectiveness of treatment. Apparently, in reality these figures are even higher, as reliable and cheap methods of controlling reception of therapy does not exist (the most effective is to monitor the content of the drug in blood plasma). In addition to reducing the effectiveness of treatment, concealment of patient from a physician in violation of medication led to mistakes in choosing subsequent treatment. Among the most common causes leading to a decrease in compliance, should be called the reluctance to accept help, fear of side effects and drug addiction, refusal of treatment for personal reasons, or delusional, the lack of a critical attitude to the disease, side effects, insufficient efficacy, lack of trust, understanding and proper contact with the doctor. The most important condition that determines adherence to therapy and quality of life of patients is tolerated, ie lack of kakihlibo unpleasant subjective experience (additional distress) associated with taking the drug. The most frequent side effects of pharmacotherapy causing distress are excessive sedation, extrapyramidal disorder (especially akathisia), weight gain, menstrual and sexual violations. Therefore, special attention should be paid to identifying the doctor these side effects, explain the need for patient medication. In this regard, it is important to develop and create products with better tolerability and the possibility of a rare admission rate. And finally, as the twelfth features should be indicated at strengthening the role etikodeontologicheskogo aspect of pharmacotherapy with the need to obtain informed consent from the patient and strict adherence to legal and ethical standards. In accordance with the law of the Russian Federation on psychiatric care and guarantees of citizens' rights in its provision physician must provide the person with a mental disorder (in a form accessible to him, and taking into account the mental state) information on the nature of mental disorder, the aims, methods, including alternative and duration of therapy, as well as pain, possible risks, side effects and expected outcomes. Physician can not in any form or exert pressure on the patient and should get it completely voluntary consent to recommended treatment. In this case, the patient signs the form, confirming that agreement, which is attached to the history of the disease. For the treatment of persons suffering from mental disorder, medical uses (including psychotropic) tools and techniques that are allowed to use the Ministry of Health, in accordance with the attached instructions. The basic structure of the modern classification of psychotropic drugs has not changed since the days of J.
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