Delay, P. Deniker (1961) (Table 3). However, it should be noted that this classification is rather conditional. between individual classes of psychotropic drugs, there are numerous transitional drugs that simultaneously possess distinct properties of both classes. These include, for example, "timoneyroleptiki (karpipramin, sulpiride)," timotrankvilizatory "(alprazolam, adinazolam), an antidepressant with a neuroleptic (amoksapin ) or nootropic (S-adenosylmethionine) properties, "trankvilonootropy (meksidol, phenibut, dipeptides pirolidinkarbonovyh acids). Some tranquilizers (lorazepam, clonazepam, phenazepam) to power its psiholepticheskogo draws to a small antipsychotics, and a number of new drugs (gepiron, fluprazin , perlapin) can simultaneously block serotonin and dopamine receptors, exerting anxiolytic and mild antipsychotic effect. Clinical practice shows that, just as one drug may be effective in a variety of states and representatives of various classes of psychotropic drugs can be successfully applied for one and the same psychopathological phenomenon. In the first case, this may be due to either the breadth of the range of psychotropic medication, or a certain commonality of the pathogenesis of some states. By means of a wide range of psychotropic action, for example, include salts of lithium and carbamazepine (finlepsin, tegretol), which are effective in maniyah , aggression, pain, etc. Some of the antidepressants (clomipramine, selective serotonin reuptake inhibitors) give quite good results not only for depression but also for obessivnofobicheskih disorders, panic attacks and other anxiety syndromes. On the other hand, many phenomenologically close depression (eg, anxiety) stoped as the use of sedative antidepressants and tranquilizers (alprazolam, clonazepam, etc.), neuroleptics (levomepromazine, tiaprid, hlorprotiksen), lithium salts or carbamazepine. This can be explained either by the fact that depression is a nonspecific clinical expression various pathophysiological processes, or the fact that different means of influence at different stages of pathogenesis of depression. Thus, the stopping fenazepama and some other benzodiazepine derivatives of acute psychotic symptoms in schizophrenic patients is probably due not so much with the true antipsychotic action, as with the impact blocking the anxiety affect, which provokes the development of psychosis. other words, the clinical reality is much more diverse than any scheme, and psychotropic properties of drugs of different classes substantially overlap. When looking at individual classes of psychotropic drugs can make the following observations. satisfactory antipsychotic effect of neuroleptics is often marred by severe neurological side effects and the almost complete lack of effect on negative symptoms and cognitive impairment.
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