This is due primarily to the extreme prevalence of these disorders, which in the general population, according to various researchers, ranging from 10% to 45%. In addition, asthenic symptoms, representing the least specific of all mental disorders are "basic" with respect to any other mental disorders, sometimes preceding or determining and almost always ending during any illness - a somatic or mental. Not by chance, even at the present stage of development of medicine marked attempts to highlight new diagnostic units asthenic states. For example, often mentioned in literature chronic fatigue syndrome, a selection of which is an attempt to attract the attention of doctors to the symptoms of fatigue. However, due to the lack of clear diagnostic criteria for this syndrome remains (as in due time "vegetative-vascular dystonia") diagnostic "slop pit", which addresses all of asthenic conditions, regardless of the characteristics of their clinical manifestations and etiopathogenesis. Separation of asthenic syndrome in neurasthenia (irritable weakness) of the XIX century (G. Beard). Table 1 shows how a classification system is coming of neurasthenia as a distinct diagnostic category. In particular, the ICD-10 in contrast to the previous (ICD-9), "getting rid" of all other neuroses, as from "a vague and undefined concepts, neurasthenia was retained as an independent nosological unit, thereby emphasizing on the one hand , the clinical reality of this state, and with others - to therapeutic approaches. Fatigue - the most common complaint with which patients come to doctors, particularly general practitioners, is the main symptom of asthenic disorders. Along with fatigue and exhaustibility they include such manifestations as irritable weakness, hypersensitivity, autonomic disorders, sleep disturbance (difficulty falling asleep, shallow sleep). Clinical typology of asthenic disorders defined by its two variants: giperstenicheskoy asthenia, characterized by hyperexcitability of sensory perception with increased susceptibility to the neutral rate of external stimuli (intolerance of sound, light, etc.), irritability, increased razrazhitelnostyu, sleep disturbances, etc., and asthenia hyposthenic whose main elements are the lowering of the threshold of excitability and responsiveness to external stimuli with lethargy, increased weakness, daytime sleepiness. Although patients and describe the asthenia as fatigue, scientific definition of asthenic state requires its delimitation from simple fatigue. In contrast to fatigue (denoted sometimes as prenosological asthenia, which is a physiological state, follows the intense and prolonged mobilizitsiey organism usually occurs rapidly and is restored after a rest, do not need medical care), asthenic conditions represents a pathological state, which emerges gradually and is due to the need to mobilize the body, lasting months or years is not reversed after rest and in need of medical care.
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