Therefore, when deciding on ...

Therefore, when deciding on the method of correction of sleep disorders should be borne in mind that sleep disorders are often a symptom of various diseases, early detection and adequate treatment of which is the basis of the treatment of sleep disorders. The indication for pharmacotherapy of sleep disorders is resistance and duration of these disorders significantly impair quality of life, even if sleep disorders are a symptom of somatic and mental diseases. Drug therapy is conducted with the ineffectiveness of the recommendations of the compliance regime, general hygienic measures. Decision-making in drug therapy of sleep disorders feasibility and indications for prescribing the drug choice, choice of the optimal dose evaluation of clinical effect of replacement of the drug in the absence of effect detection of possible side effects and their correction Length medication choice of hypnotic drug · clinical situation (age, underlying disease, medications, etc.) · pharmacological activity of hypnotic · pharmacokinetics · Interaction with other drugs in drug choice should be guided by the basic requirements for the so-called ideal hypnotic. In this case, the drug should cause a rapid fall asleep in the lowest dose, do not have advantages in increasing doses, which would allow to avoid increasing the dose by the patient, reduce the number of nighttime awakenings. At the same time, the drug should not reduce the quality of ? ? daily life of the patient, do not affect his mood, performance, and other routine daily activities. Currently, the arsenal of the practitioner, there are three generations of hypnotics belonging to different classes and having different mechanisms of action, efficacy, tolerability, safety. The first generation of hypnotic barbiturates, antihistamines, propanediol, chloral hydrate, paraldegit. The second-generation derivatives of benzodiazepines (Nitrazepam, flurazepam, Temazepam, midazolam, etc.). The third generation nebenzodiazepinovye hypnotics, including derivative tsiklopirrolonov (zopiclone) and derivative imidazopiridina (zolpidem). First-generation drugs currently available for treatment of sleep disorders are practically not used and should not be used in accordance with their side effects and complications from chronic administration. You should not use drugs that have the hypnotic effect is not the main (antihistamines, tricyclic antidepressants, etc.), and their appointment may lead to a number of side effects, especially when patients with concomitant diseases (glaucoma, benign prostatic hyperplasia), is a contraindication to their purpose. Opening the second half of the twentieth century, drugs belonging to the class of drugs, and the development of drugs with hypnotic effect (trankvilizatorygipnotiki) significantly changed the situation in the treatment of sleep disorders.