Patients received either a daily basis ...

Patients received daily either 400 mg Actovegin, or placebo. At the 6 th and 12 th weeks of the study assessed the efficacy and tolerability of therapy. Treatment efficacy was assessed by changes in common clinical manifestations of dementia observed by doctors. Medical reports were compiled on a standard scale of overall clinical assessment (Clinical Global Impression Scale) - adopted by the worldwide method of evaluation of clinical change. Additionally conducted a short test syndromic (Short Syndrome Test), commonly used to assess memory and attention. This test helps diagnose assess the severity of dementia. Another method of evaluation is the Nuremberg age scale (NVSH), which was designed for people who speak German. She, among other things, allows patients to the older age groups to assess their own state, it is important to analyze the cognitive abilities of patients. With these tests, you first need was to assess the need of patients in home care, which reflects the ability of patients in daily self care. In addition, we studied the social activity of patients. The study included patients with mild to moderate dementia. The diagnosis of "dementia" was installed in accordance with the criteria of the International Classification of Diseases, revision X, and stood out such forms of dementia, as sporadic dementia of Alzheimer type (LET), vascular dementia (SD) and mixed type of dementia. The severity of dementia was placed on a short test of syndromal and mini-mental status tests (Mini Mental State Examination - MMSE) was used for evaluation of cognitive disorders, disorders of orientation in space and time, attention, speech and thought. Also, the criteria for inclusion included figures from 6 to 18 points on a scale of TCS, and from 16 to 26 points on the MMSE-point scale. Patients with impaired consciousness, depression, psychosis, epilepsy and other types of dementia were excluded from the study. Medications that might influence the studied parameters, such as psychostimulants, nootropic drugs, or vasoactive substances are not allowed. In general, the results analyzed data on 200 patients enrolled in the study. Between the placebo group and the core group showed no significant demographic differences. The most common concomitant diseases are diseases of the musculoskeletal system. The majority of patients were diagnosed with mild dementia, in numerical scale MMSE - between 19.9 and 20.1 points. For all three parameters used in the comparative analysis, it was noted a distinct improvement under the influence of Actovegin. At the end of a six-week period of therapy in 22% of patients treated with gemodializatom calf blood, was a significant improvement in general condition, documented on 2 nd item of the scale of the total clinical evaluation.