It is a combination ...

It is a combination of d-wave and high-amplitude a-rate, lower in frequency by 1 - 2 fluctuations than in wakefulness, and takes up to 1 / 5 of total sleep time. The depth of sleep, defined at a higher threshold for arousal, is greater than in stage II. It has been suggested that short bursts d-waves are mikroperiodami deep slow wave sleep. Violation of laws of distribution of d-activity and a reduction in its amplitude and intensity indicate the relationship of mechanisms of FMS and D. This is consistent with the hypothesis that the synthesis and accumulation of brain noradrenaline (NA) is performed during the FMS and D, characterized by a deficit on, is observed reduction of stage IV sleep. Isolation of French researchers dofaminzavisimoy D, which proved to be most sensitive to dofaminomimetikam than other antidepressants, conducted including the use of indicators disorders of sleep structure, similar to what happens in patients with Parkinson's disease. Obtained further evidence showed, however, that violations of d-sleep with A more typical for men and are not specific only to D. A significant fluctuations in the duration of stage IV sleep, age-related, in particular its substantial reduction in adulthood and especially in elderly. At A Observed and PBS. According to various reports, patients with D there is considerable variation duration PBS -: from 16,7 to 31%. The most important indicator that reflects the magnitude of the need for PBS, is considered its latent period (LP). The phenomenon of reduction of LP when A has long attracted the attention of researchers. Reducing LP PBS series of the authors saw as a sign of increased activity of devices that generate this phase of sleep and associated with an increased need for fast sleep. It is shown that the D than the expression, the greater the degree of REM going into "packets" between which there are long periods without any oculomotor activity. However, other data suggest simply increasing the density of REM sleep in the first few cycles. There are reports that the reduction of PL of PBS is not equally characteristic of different types of AD have shown that short LP is characteristic only for all the primary D and absent in the secondary. However, he does not determined by other parameters of sleep and not depend on age and action of drugs. It is shown that typical patients with endogenous A (60% with an index of specificity 70%) is the reduction of PL of PBS and 70 min. It is possible that these data indicate desynchronization of circadian rhythms in the cycle of sleep - waking and shift to an earlier time. These changes are associated with the deep mechanisms of endogenous DA is also possible that the characteristic changes in sleep by themselves play a role in the pathogenesis of AD Some authors emphasize the link between the nature and severity of dreams with the quantitative and qualitative changes in the FBS in patients with AD In endogenous temporal organization of the D cycle of REM sleep - REM sleep was significantly impaired.