Publications covering the use of ...

In modern psychiatry, including anxiety and phobic states of panic disorder occupies a special place. Panic attacks by type of vegetative crises syndrome (Da Casta, aleksitimicheskaya panic ") accounted for 60% of panic disorders. The predominance of somatic anxiety, phobias, hypochondriacal, depressive experiences justify the use of antidepressants with minimal side effects have balanced both anxiolytic and stimulating action. Paxil, manufactured by the pharmaceutical company "Smith Kline Beecham" (UK), refers to a group of selective inhibitors of reverse neuronal serotonin reuptake and satisfies the requirements. In the foreign psychiatric literature is marked clinical efficacy of Paxil as compared with tetracyclic antidepressants [4, 5]. Domestic studies of antidepressant activity of this drug are not numerous and are mainly dedicated to treatment of endogenous depressions of moderate to severe intensity [2, 3]. Psychotropic activity of Paxil has its own characteristics that define the indications for its individual purpose and deserve close attention. Publications covering the use of paroxetine in the treatment of anxiety disorders are rare. Pathogenetically justified the use of antidepressants in panic attacks and agoraphobia due to its anxiolytic and antifobicheskogo action. According to some authors, paroxysmal anxiety completely stoped at 46,2% patients and 50% were reduced in 29.6% of patients [1]. On the base of the Republican Clinical Hospital, MOH, we used Paxil in a dose of 20 mg. per day to 60 mg. daily as monotherapy and in combination with neuroleptics, and cerebroprotector vazotropnymi drugs for relief of depressive symptoms in four women, one of whom suffered panichekim disorder. To evaluate the effectiveness of treatment methods were used: clinical observation of the dynamic, instrumental, laboratory and psychological examination. Further assessment of the patients and psycho-dynamic parameters was performed using the international scale of the Hamilton Depression and Anxiety (HAMD, HAMA) Depression Scale Montgomery - Asberg (MARDS), Beck Depression Inventory questionnaire (BDI) before therapy, after a week and at the end of the course. Side effects of the drug were monitored using a scale of side effects (SARS).     

The longest and most effective course of therapy was paksilom panic disorder. Paroxetine was administered in a single daily dose of 20 mg. 3 weeks in hospital, at the same dose the patient continued to take its outpatients for 2 months.

G., 1934, "Mixed anxiety and depressive disorders" F 41.2 2 years 2 years hypo-timiya neuro-energy levels with psychogenic, medically, is due-governmental wave-shaped fluctuations affect manifestation provoked after anesthesia true dientsefalnyh crise with the formation of Pani-crystal-type attacks vegetative crises, persistent phobias, and overvalued hypochondria, avoidant behavior, gentle lifestyle Panic attacks with a frequency of 2 -3 times a week., conversion symptoms and somatic anxiety, involving cardio-vascular and respiratory systems, overvalued hypochondriacal phobias, depression, mild, formal criticism.