It gipoestrogennoe status in patients with anorexia nervosa is the basis of their susceptibility to osteoporosis. His weight is determined by the duration gipoestrogenemii. In connection with violations of gonadotropic and metabolic hormones, patients with anorexia nervosa in hormonal terms as would be returned to the prepubertal state. In this case, reproductive disorders should be regarded as a defensive response in terms of food shortages and mental exertion. So for the restoration of the age of secretion of gonadotrophic releasing hormone is required to achieve ideal body weight and the elimination of mental stress. Along with gipoestrogenemiey anorexia nervosa is characterized by an increase in blood cortisol (adrenal hormones), emitting its excess in the urine, as well as reduced thyroid hormones - thyroxine (T4) and T3. Which takes place in anorexia nervosa insufficient caloric intake may cause increase in growth hormone levels. Clinical manifestations of Anorexia nervosa in 50% of the cases can proceed episodes of bulimia, after which the patient often particularly obvious signs of anxiety, remorse and depression. The development of bulimia nervosa in patients with anorexia may indicate that innate factors and the influence of social environment act as a kind of counterweight biopsihologicheskogo aimed at combating starvation and maintenance of body weight. Clinical manifestations of anorexia nervosa have their own characteristics: predominance of adolescent girls (described only isolated cases of prepubertal boys) compliance with strict dieting adolescents with obsessive quest for weight loss, often leading to a drastic depletion depends on the degree of weight loss and poor tolerance to cold, especially , heat, abnormal fear of lose control of food intake and body weight binge (bulimia) and the artificial stimulation of the vomiting, excessive, compulsive self-affirmation of incorrect self-esteem with the loss of ability to distinguish between the thickness and thinness decrease in body temperature (chill) drop in blood pressure (hypotension), loss of menstruation (amenorrhea) - an important symptom that may appear before the lower body weight, and at the same time or after weight loss These features differentiate anorexia nervosa from a "simple weight loss, or aversion to food and weight loss in diseases such as hypopituitarism (insufficient pituitary cells , thereby reducing the production of hormones). Patients with anorexia nervosa in typical cases, aggressive and focused on themselves, have an internal psychological conflict and ill-adapted to the environment. Treatment and outcome of most patients seek medical attention before the onset of severe malnutrition. In such cases, recovery can occur spontaneously without medical intervention. If, however, patients need medical care, it has traditionally included psychoanalysis, psychotherapy, coaching members of the family and forced feeding.
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