Security broader category that overlaps portability. It also includes the absence of a negative effect on metabolic processes, the functions of individual organs and systems, which is particularly significant during prolonged therapy. Following the recommendations of the so-called Compliance, ie agreement, coherence patient and physician important factor for successful therapy. Usually not less than 1 / 3 therapeutic recommendations are not fully implemented, violations of regularity and precision of the prescribed purposes. Alignment is especially important in ambulatory practice, where the function of monitoring therapy largely passed, "delegate" to the patient, of course, necessarily prepared for it. References: 1. Avrutsky GY Neduva A. M. Treatment of Mental Illness: Science, 1984. 2. Report on world health 2001.Psihicheskoe Health: New Understanding, New Hope. WHO, 2001 3. Clinical Manual: Models of diagnosis and treatment of mental and behavioral rasstoroystv Ed red.V.N.Krasnova and IY Gurovich. M.: Application of the journal "Social and Clinical Psychiatry, 1999 4. KornetovN.A.Depressivnye disorder. Systematics, diagnostics, semiotics, therapy. Tomsk.: Siberian Publishing House, 2001 5. Krasnov VN The organizational model of care to those suffering from depression, in terms of territorial polikliniki.Metodicheskie rekomendatsii.M: Ministry of Health Rossii.2000. 6. Krasnov VN Psychiatric disorders in general medical praktike.Russky Medical zhurnal.2001.tom9.N 25.s.1187-1191 7. Mosolov SN Clinical use of modern antidepressants. SPb.: Medical News Agency 1995. 8. Educational Program on Depressive Disorders. Module 1. Overview and Main Aspects, World Psychiatric assotsiatsiya.Per. with angl.M.: Eli Lilly Vostok, 1999. 9. Smulevich AB Kozyrev VN Syrkin AL Depression in the medically ill. Moscow: 1997 10. Smulevich AB Depression in general medicine. M.2001 11. Federal guidelines for physicians on the use of drugs (Formulary System). Release P., 2001 12. Bech P. Pharmacological treatment of depressive disorders: A review. Depressive Disorders. Eds. M. Maj, N. Sartorius. Chichester etc: Wiley.1999, pp.89-127 13.Carney RM, Freedland KE Major depressive disorder predicts cardiac events in patients with coronary artery disease. Psychosom. Med. 1988, v.50, pp.627-633 14.Glassman AH, Pierse DW Treatment of depression in patients with heart disease. J. Pract. Psychiat.a.Behav.Health., 1998, v.4, pp.140-149 15.Katon W., Sullivan MD Depression and chronic mental illness. J. Clin. Psychiatry, 1990, v.51, pp. 3-11 16.Lesperance F. et al. Major depression before and after miocardial infartion: its nature and consequences. Psychosomatic Medicine, 1996, v. 1958, pp.99-110 17.Lyness J.M. et al. Depressive symptoms, medical illness and functional status in depressed psychiatric inpatients. Am.J. Psychiatry. 1993, v. 150, pp.910-915 18.Moeller HJ (Hrsg) Therapie psychhiatrischer Erkrankungen.Stuttgart: Enke Verlag, 1993 19.Murray Ch.JL, Lopes AD
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