Reducing the possibility of ...

Benefits of rehabilitation therapy, as restoration of the old social role and professional abilities of the patient, actually appeared only in the last decade. This is due to the fact that, along with justified itself when expressed, severe depression, tricyclic antidepressants appeared several new pharmacological group of antidepressants. Their advantages and benefits compared with tricyclic compounds are due not so much the power of antidepressant action (here, they often yield tricyclic antidepressants), but significantly less severe side effects, respectively, more robust security. It is side effects, including cardiotoxic, hepatotoxic, neurotoxic, limit the scope of today, such high-tricyclic antidepressants as amitriptyline, imipramine, irreversible MAO inhibitors. Above all, these restrictions apply to general medical practice. However, the modern choice of antidepressants (the major ones are listed in Table. 2) is quite wide. Many of these facilities have no significant side effects and under certain conditions can be successfully applied in the general profile settings and primary care network. Affiliation antidepressant to a particular subgroup is determined by its chemical structure, but does not always correlate with its ultimate pharmacological effect. For example, antidepressants, SSRIs and SSOZS opposite effects on certain receptor systems, are considered to be associated with depression, but they both eventually have antidepressant effects. Many antidepressants are polyvalent in effects on different neurotransmitters - serotonin, norepinephrine, dopamine and related receptor systems. Scattered atypical antidepressants are sometimes referred to various groups or define as modulators of serotonin receptors - such as trazodone [12]. Preference is given to modern treatment of depression drugs with less side effects. In addition, many of today's vehicles may be taken 1-2 times per day, which is important in long-term outpatient treatment. Taken into account when choosing a drug known features of the therapeutic effect of an antidepressant: a balance of tianeptine and maprotiline, mirtazapine, milnacipran, the presence of an activating component of the antidepressant activity of selective serotonin reuptake inhibitors - fluoxetine, sertraline, paroxetine, to a lesser degree of citalopram and fluvoxamine ( the latter can be protivotrevozhnoe and action), a combination of proper antidepressant (timoanalepticheskih), anxiolytic (tranquilizing, calming) vegetostabiliziruyuschih properties of Mianserin. Well use it when expressed anxiety autonomic manifestations of depression, the presence of a soporific effect during persistent insomnia with trazodone, marked effectiveness in apathy and anergy of moclobemide.