Thursday, 22 September 2011

For these purposes for decades ...

For these purposes for decades ...

For these purposes for decades used a variety of hypnotics and sedatives, as well as combinations thereof. Particularly effective was the combination of ethanol with barbiturates. The proposed EA Popov (1935), a mixture of ethyl alcohol and pentobarbital are still being used successfully for relief of alcohol withdrawal syndrome and delirium tremens. The use of ethanol seems to be quite reasonable, because delirium, the modern view, is the most difficult the withdrawal syndrome. Later it became clear that the more effective is the combination of sodium amytal and alcohol. Usually prescribed phenobarbital or 0.4 0,50,6 amytal with 4050 ml of 40 ? ethyl alcohol. Mixture is given repeatedly to achieve the long hours of sleep. With the advent of tranquilizers found that perfect effect can give an introduction to 2,040 mg of diazepam or 200 400 mg of meprobamate. Diazepam (relanium) was the preferred drug, especially intramuscular or intravenous injection. Abroad, and then in our country, is widely used hlormetiazol. Especially effective is the slow drip 500 ml 0.8% solution hlormetiazola. Hlormetiazol used in minor surgery for raushnarkoza. The ability of the drug to cause a deep sleep has been very valuable for the relief of delirium. Of course, the introduction of hlormetiazola requires continuous monitoring of the patient because of possible during anesthesia breathing stops. In domestic Addiction successfully used a slow (drip) the introduction of 3040 ml of 20% solution of sodium oxybutyrate. Typically, first introduced in 2040 mg of diazepam, then oxybutyrate sodium. Oxybutyrate sodium is valuable, which increases the endurance of the brain to hypoxia, occurring during a delirium, and quickly released from the body. For relief of delirium and used some funds for anesthesia. So, delirium were cut by i / m injection of 10 ml of 10% solution of hexenal or 10 ml of 2% or 5% solution of thiopental sodium. Usually for the renewal of these drugs in the enema was administered sodium amytal 0.5. Made also unsuccessfully attempted to use general anesthesia using nitrous oxide. Used and various combinations of drugs that have had a sedative and hypnotic effects. So, effectively a combination of 0.5 amytal with diphenhydramine 50 mg or 50 mg of diphenhydramine 50 mg prometizina. Of the neuroleptics used chlorpromazine, butyrophenone. It turned out that the use of powerful aadrenolitikov best avoided because of the possible fall in blood pressure. However, intramuscular injection of 1015 mg of haloperidol is very often leads to a decrease in excitation onset of sleep. In relieving delirium usually resort to a combination of several drugs. So, has spread the technique proposed VI Sema et al (1985). According to this methodology consistently introduce the following products: a mixture of Popov (40 ? alcohol from 0,4 phenobarbital) 100 150 ml, 48 ml of 0.5% of diazepam intravenously, 4050 mL of 20% solution of sodium oxybutyrate intravenously, 10 ml of 5% solution of Amity intramuscularly , 15 mg of haloperidol intramuscularly.

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