Side effects of drugs is ...

Side effects of medications is weak to moderate dry mouth, drowsiness and sedation in the first week of admission, which is typical for most vehicles with antihistamine effect. These side effects are minimal at gradually increasing doses (ranging from 12.5 mg once at night and increasing the dose to 12.5 mg every day to an average dose of 50 mg divided into 2-3 doses) and completely pass at the reception. Hydroxyzine is an important feature of the aftereffect, ie, saving effect of the drug after its withdrawal, without the development of withdrawal syndrome [56]. All this makes hydroxyzine useful for long-term use in patients with GAD in general practice (especially those with concomitant somatic pathology). Abroad for the treatment of GAD is widely used partial agonist, serotonin receptor 1A - buspirone [10,12], but in Russia it is not currently available. Often, to avoid benzodiazepines in patients with GAD designate small antipsychotics (eg thioridazine), but controlled studies to support the use of neuroleptics for GAD is very small [29], and the small antipsychotics are non-existent. In addition, studies of neuroleptics were mostly to do with "pure" GAD, and in patients with comorbid mental disorders. For these reasons, as well as the extrapyramidal side effects, even small doses of neuroleptics International Group to develop a consensus on the GAD did not include them in the list of drugs recommended for long-term treatment of GAD [12]. Conclusion GAD - a very common mental disorder c chronic, undulating course, spontaneous remission is observed only a third of patients. It causes the same reduction in disability and quality of life, depression, and weights for concomitant somatic diseases, leading to an increase in the cost of doing such patients. GAD requires prompt diagnosis and effective therapy purposes, including doctors somatic specialties. References 1. Avedisova AS Anxiety disorders. In: Alexander Y. "Mental disorders in general practice and their treatment." M: GEOTAR-MED, 2004. S. 66 - 73. 2. Bobrov, AE, Belyanchikova MA, OA Gladyshev et al. Atarax drug in outpatient treatment of anxiety states. Soc. and the wedge. Psychiatry, 1998, vol.8, no. 1, p.63-67. 3. GI Kaplan, BJ Seddok. Clinical Psychiatry. Moscow: Medicine. - 1994. 4. Smulevich AB Depression in general medicine: a guide for physicians. - MA MSA, 2001. 5. Churkin AA, AN Martushov A brief guide to using ICD-10 in Psychiatry and Addictions. M.: Triada-X, 1999. 6. Allgulander C, Nilsson B. A nationwide study in primary health care: One out of four patients suffers from anxiety and depression. Lakartidningen. 2003 Mar 6; 100 (10) :832-8 7. Andrews G, Henderson S, Hall W. Prevalence, comorbidity, disability and service utilisation: overview of the Australian National Mental Health Survey.