The influence of the drug on memory function showed the beneficial effects of the drug on memorization, the consolidation and reproduction of information, was an improvement of attention and daily activity of elderly patients [14]. Study of efficacy and tolerability in the treatment of Enerion asthenic disorders in patients of elderly conducted in the Department for the Study of Alzheimer's disease and associated with her disorder Mental Health Research Center of RAMS. The study included patients aged 60 years and older, under the supervision of the cabinet gerontopsihiatricheskogo somatic territorial polyclinics. Identified in patients with asthenic disorders included in the structure psychoorganic syndrome, cerebro-vascular origin, due to psychogenic asthenic conditions or concomitant manifestations of these disorders. Treatment Enerionom an outpatient in an open uncontrolled study. The drug was administered orally at 200 mg tablets, a single (daily) dose was 400 mg once daily in the morning after a meal. Treatment Enerionom held within a month. Subjects vklyuchal28 patients (2 males and 26 females) aged from 62 to 84 years. The average age of patients was 71 ± 5,8 years. Clinico-nosological evaluation asthenic disorders in the studied patients were as follows. In the 22 observations asthenic (psevdonevrastenicheskie) symptoms measured pattern of the initial psychoorganic syndrome in cerebro-vascular diseases with manifestations of hypertensive encephalopathy dyscirculatory / atherosclerotic type and combined in some cases with symptoms of mild cognitive dysfunction (dismnesticheskie disorder phenomena bradipsihizma) in the presence of so-called "vascular complaints (headache, dizziness, tinnitus, etc.). In the remaining 6 cases asthenic disorders were formed in the reactions of maladaptation in response to stressful or somatogenically virtues. Asthenic disorder characterized by complaints of a painful feeling with the constant feeling of weakness, fatigue, exhaustion, rapid onset of fatigue with minimal load, with the need for extra rest, the desire to be in the daytime, and the rest did not bring any significant relief. The overall decline in activity, performance was accompanied by some decrease in the mood to dissatisfaction with himself, sometimes with samouprekami of inactivity or repeated postponement of cases requiring tension and concentration, in anticipation of the appearance of strength "after the holidays, usually to no avail. Sense of physical weakness combined with exhaustibility mental processes that showed up in the irritable weakness, impatience, emotional lability with a penchant for high sensitivity, touchiness about trifles, tearful reactions, sometimes in the form of incontinence tears in response to any stimuli.
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